• Jing-Huei Lee, PhD
  • Associate Professor
  • Education: PhD, 1993 State University of New York, Stony Brook
  • Office: MSBSVC-E681D
  • Tel: 513-558-5676
  • Email: jing-huei.lee@uc.edu
  • Personal Webpage

Dr. Lee is an Associate Professor in the Departments of Biomedical Engineering at the University of Cincinnati. Before joining the Department of Biomedical Engineering at UC, Dr. Lee was a chemist at the Brookhaven National Laboratory in Upton, NY. His current research interests focus on the development of magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) techniques. He is currently the Associate Director of the Center for Imaging Research.

Research Interests

Development of magnetic resonance imaging (MRI) and spectroscopy (MRS) methodologies and the utilization of these methodologies for studying metabolism, bioenergetics and function of the brain and other organs noninvasively.

Current Research Projects

4 Tesla Magnetic Resonance Imaging (MRI) and Spectroscopic (MRS) Studies of Human Subjects

The aim of this study is to develop new magnetic resonance imaging (MRI) and spectroscopic (MRS) radiofrequency (RF), field gradient pulse sequences, as well as functional MRI (fMRI) stimulus paradigms. These pulse sequences promise higher spatiotemporal resolution, better contrast, new pathophysiological specificity, or other advantages over pre-existing pulse sequences, leading to better image quality and increased scientific information from images.

Selected Recent Journal Publications

  • J.-H. Lee, and C. S. Springer Effects of equilibrium Exchange on Diffusion-Weighted NMR Signals: The Diffusigraphic "Shutter-Speed", Magnetic Resonance in Medicine, 49, 450-458 (2003).
  • P.K. Thanos, N.B. Taintor, D. Alexoff, J. Logan, D.K. Grandy, Y. Fang, J.-H. Lee, J.S. Fowler, and N.D. Volkow, In Vivo Comparative Imaging of Dopamine D2 Knockout and Wild-Type Mice with (11)C-Raclopride and MicroPET, The Journal of Nuclear Medicine 43, 1570-1577 (2002).
  • M. D. Silva, K. G. Helmer, J-H. Lee, S. S. Han, C. S. Springer, and C. H. Sotak, Deconvolution of Compartmental Water Diffusion coefficients Using Combined T1 and Diffusion Measureements, Journal of Magnetic Resonance 156, 1-12 (2002).
  • J.W. Pan, F. Telang, J-H. Lee, R. A. DeGraaf, D. L. Rothman, H. P. Hetherington, Acute Hyperketonemia Raises Brain b-hydroxybutyrate, Journal of Neurochemistry 79, 539-544 (2001).
  • R. A. DeGraaf, J.W. Pan, F. Telang, J-H. Lee, P. Brown, E.J. Novotny, H. P. Hetherington, D. L. Rothman, Differentiation of Glucose Transport in Human Brain Gray and White Matter, Journal of Cerebral Blood Flow Metabolism 21, 483-492 (2001).
  • J-H. Lee, PURR-TURBO: A Novel Pulse Sequence for Longitudinal Relaxographic Imaging, Magnetic Resonance in Medicine 43, 773-777 (2000).
  • J-H. Lee, X. Li, M. K. Sammi, and C. S. Springer, Using Flow Relaxography to Elucidate Flow Relaxivity, Journal of Magnetic Resonance 136, 102-113 (1999).
  • J-H. Lee, M. Garwood, R. Menon, G. Adriany, P. Anderson, C.L. Truwit, and K. Ugurbil, High Contrast and Fast Three-dimensional Magnetic Resonance Imaging at High Fields Magnetic Resonance in Medicine 34, 308-312 (1995).

Selected Peer Reviewed Proceedings and Presentations

  • S.R. More, T.C. Lim, C. K. Holland and J.-H. Lee, Characterization of the acoustic noise response of a 4T MRI scanner, Proc. Int. Soc. Magn. Reson. Med. 12, 1660 (2004), Twelfth Annual Meeting of the International Society for Magnetic Resonance in Medicine; Kyoto, Japan, May 15-21, 2004.
  • Z. Peng, W. Wee, J. Zhong, and J.-H. Lee, Segmentation of B1 inhomogeneity MR brain image using mixture Gaussian model and Markov random field, Proc. Int. Soc. Magn. Reson. Med. 12, 2231 (2004), Twelfth Annual Meeting of the International Society for Magnetic Resonance in Medicine; Kyoto, Japan, May 15-21, 2004.
  • J.W. Pan, L. Krupp, J-H. Lee, P. Melville, and H. Hetherington, Spectroscopic Measures of Cognitive Fatigue in Multiple Sclerosis, Proc. Int. Soc. Magn. Reson. Med. 10, 1202 (2002), Tenth Annual Meeting of the International Society for Magnetic Resonance in Medicine; Honolulu, Hawaii, USA, May 18-24, 2002.
  • J-H. Lee, Saturation Steady-State Weighting of MRI Intensity: Tracking Instantaneous T1 Changes, Proc. Int. Soc. Magn. Reson. Med. 9, 2254 (2001), 9th Annual Meeting of the International Society for Magnetic Resonance in Medicine; Glasgow, Scotland, UK, April 21-27, 2001.
  • J.W. Pan, J-H. Lee, F. Telang, I. Gabriely, Robin De Graaf, M. K. Sammi, D. T. Stein, D.L. Rothman and H.P. Hetherington, Measurement of Human Brain b-hydroxybutyrate in Acute Hyperketonemia, Proc. Int. Soc. Magn. Reson. Med. 9, 384 (2001), 9th Annual Meeting of the International Society for Magnetic Resonance in Medicine; Glasgow, Scotland, UK, April 21-27, 2001.
  • J-H. Lee, F.W. Telang, C. S. Springer, Jr., and N.D. Volkow, 4T fMRI Evaluation of Cerebral Blood Vessel Function in Cocaine-Dependent Subjects, Proc. Int. Soc. Magn. Reson. Med. 9, 433 (2001), 9th Annual Meeting of the International Society for Magnetic Resonance in Medicine; Glasgow, Scotland, UK, April 21-27, 2001.
  • J-H. Lee, D.C. Medina, X. Li, F.W. Telang, P.L. Micca, J.A. Coderre, and C. S. Springer, Jr. Deuterium Quenching of 1H2O Relaxation in the Living Rat Brain, Proc. Int. Soc. Magn. Reson. Med., 9, 529 (2001), 9th Annual Meeting of the International Society for Magnetic Resonance in Medicine; Glasgow, Scotland, UK, April 21-27, 2001.
  • H.P. Hetherington, J-H. Lee, M. K. Sammi, and J.W. Pan, Quantitative Spin Echo 31P Spectroscopic Imaging in Human Brain: Determination of the Free Energy of ATP Hydrolysis, Proc. Int. Soc. Magn. Reson. Med. 9, 217 (2001). 9th Annual Meeting of the International Society for Magnetic Resonance in Medicine; Glasgow, Scotland, UK, April 21-27, 2001.
  • J-H. Lee, M. K. Sammi and C. S. Springer, Flow Relaxographic Angiography, Proc. Int. Soc. Magn. Reson. Med. 8, 1828 (2000), 8th Annual Meeting of the International Society for Magnetic Resonance in Medicine; Denver, CO, April 1-7, 2000.
  • J-H. Lee, J. M. Brener, J. M. Sniffen, G. Hudson and C. S. Springer, The fMRI Responses Associated with Static Force Contractions in the Human, Proc. Int. Soc. Magn. Reson. Med. 8, 608 (2000), 8th Annual Meeting of the International Society for Magnetic Resonance in Medicine; Denver, CO, April 1-7, 2000.
Copyright Information © 2008 University of Cincinnati Center for Imaging Research